求生命科学SCI文献一篇

热心网友：RNA-directed DNA methylation 期刊 Plant Molecular Biology 出版社 Springer Netherlands ISSN 0167-4412 (Print) 1573-5028 (Online) 期 Volume 43, Numbers 2-3 / 2000年6月 DOI 10.1023/A:1006479327881 页 203-220 学科分类 生物医学和生命科学 Springerlink Date 2004年12月15日 添加入标记条目中 添加入购物车 添加入收藏条目中 Permissions & Reprints 推荐此文章 PDF (217.8 KB) RNA-directed DNA methylationMichael Wassenegger1 (1) FhG Molekulare Biotechnologie, Am Klopferspitz 18A, 82152 Martinsried, Germany Abstract RNA-DNA interactions can serve as a signal that triggers de novo DNA methylation in plants. As yet, this RNA-directed DNA methylation mechanism merely targets transgenes, but it appears likely that methylation of some endogenous sequences is also directed by RNA. RNA-directed methylation of cytosine residues specifically occurs along the DNA regions that are complementary to the directing RNA pointing to the formation of a putative RNA-DNA duplex. Dense methylation patterns and the methylation of cytosine residues at symmetric and asymmetric sites are detectable on both DNA strands within these regions. Methylation progressively decreases in the sequences adjacent to the putative RNA-DNA duplex. The extreme sensitivity of RNA-directed DNA methylation was demonstrated by analysing a short 30 bp DNA region that was complementary to the targeting RNA. Association of RNA-directed DNA methylation with homology-dependent gene silencing indicated that the methylation-directing RNA molecules may be double-stranded or may contain double-stranded regions. Whereas the function of DNA methylation in transcriptional gene silencing is nearly understood, its role in post-transcriptional gene silencing is still under discussion. In mammals, X-chromosome inactivation and genomic imprinting are associated with DNA methylation but how methylation is initiated is unclear. The observation of a correlation between specific antisense RNAs and transcriptional and post-transcriptional gene silencing may indicate that RNA-directed DNA methylation is involved in epigenetic gene regulation throughout eukaryotes.5-methylcytosine - RNA-directed DNA methylation - RNA-DNA hybrid - RNA-directed RNA polymerase - viroids--------------------------------------------------------------------------------Michael WasseneggerEmail: wasseneg@biochem.mpg.de Fulltext Preview (Small, Large) 这个只有第一页http://www.springerlink.com/content/t50w166353u61q73/你可以写邮件和作者索取wasseneg@biochem.mpg.de

热心网友：1、使用sci查找综述文献检索思路为：主题（biomass energy）与 文献类型（review）。 2、使用cnki查找中文文献检索的基本思路就是：主题（生物质能）与 题名（综述 或 进展或概况或概述），针对该数据库一个检索途径下可以输入两个检索词的具体情况，其检索式可以这样构造： ((题名=概述 或者 题名=概况) 或者 (题名=综述 或者 题名=进展))and (主题=生物质能)) 3、使用ei查找外文文献检索思路是：主题（biomass energy）与题名（review）以上简要说明了综述文献基本的检索方法，实际的文献需求更为复杂，相应的检索式也要复杂一些，比如复杂的研究主题需要逻辑组配、相近概念的逻辑组配等等。检索者可根据自己的文献需求和实际的检索情况做相应的调整。

热心网友：没有诶，名字不对吧？

热心网友：楼主给下文献的作者名字